Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.47 |
| ▸ | AHR | P35869 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | DNM2 | P50570 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627754 | 0.93 | RAB9A (0.49) | F10AHRHDAC1MEN1KMT2A | |
| SCHEMBL16627880 | 0.89 | HDAC1 (0.47) | F10HDAC1MEN1KMT2AMAPT | |
| SCHEMBL16627814 | 0.89 | F10 (0.48) | F10AHRMEN1KMT2AMAPT | |
| SCHEMBL16627656 | 0.87 | F10 (0.47) | F10AHRMEN1KMT2AMAPT | |
| SCHEMBL16627753 | 0.85 | ABCG2 (0.51) | F10MEN1KMT2AMAPTNPC1 | |
| SCHEMBL16627824 | 0.82 | MEN1 (0.47) | AHRMEN1KMT2AMAPTNPC1 | |
| SCHEMBL16627685 | 0.82 | MEN1 (0.47) | F10MEN1KMT2AMAPTKDM4E | |
| SCHEMBL16627806 | 0.79 | NHERF1 (0.49) | F10MEN1KMT2AMAPTGAA | |
| SCHEMBL16627877 | 0.79 | MAPT (0.47) | F10HDAC1MEN1KMT2AMAPT | |
| SCHEMBL16627749 | 0.76 | MEN1 (0.58) | MEN1KMT2AMAPTNPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |