Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.42 |
| ▸ | CNR2 | P34972 | 10/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627705 | 0.76 | MEN1 (0.49) | CNR1CNR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16627581 | 0.70 | CNR1 (0.54) | CNR1CNR2LMNA | |
| SCHEMBL16627827 | 0.67 | AHR (0.49) | CNR1CNR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2736472 | 0.66 | CNR2 (0.51) | CNR1CNR2MAPTLMNATP53 | |
| SCHEMBL16627829 | 0.65 | KMT2A (0.49) | CNR1CNR2SMN1; SMN2MAPTLMNA | |
| SCHEMBL16627835 | 0.64 | CNR1 (0.48) | CNR1CNR2MAPTL3MBTL1HPGD | |
| SCHEMBL16627770 | 0.64 | KMT2A (0.57) | SMN1; SMN2MAPTLMNATP53 | |
| SCHEMBL11053552 | 0.63 | CA1 (0.56) | CNR1CNR2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2737020 | 0.63 | CNR2 (0.91) | CNR1CNR2 | |
| SCHEMBL11050202 | 0.62 | CA1 (0.60) | SMN1; SMN2NPC1RAB9AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |