Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627770 | 0.75 | KMT2A (0.57) | AHRKDM4ESMN1; SMN2TP53KMT2A | |
| SCHEMBL16627705 | 0.72 | MEN1 (0.49) | SMN1; SMN2NPC1RAB9AKMT2ACNR2 | |
| SCHEMBL16627829 | 0.72 | KMT2A (0.49) | AHRKDM4ESMN1; SMN2TP53KMT2A | |
| SCHEMBL16627590 | 0.72 | NPC1 (0.49) | AHRRXFP1KDM4EMAPK1HTT | |
| SCHEMBL16627581 | 0.70 | CNR1 (0.54) | AHRKDM4EKMT2ACNR2CNR1 | |
| SCHEMBL16627834 | 0.70 | KMT2A (0.53) | KDM4EHTTSMN1; SMN2TP53KMT2A | |
| SCHEMBL5434347 | 0.70 | RECQL (0.56) | AHRRXFP1KDM4ETP53NPC1 | |
| SCHEMBL16627676 | 0.69 | P2RX4 (0.52) | AHRKDM4EMAPK1SMN1; SMN2KMT2A | |
| SCHEMBL16627830 | 0.68 | CNR1 (0.47) | AHRKDM4ESMN1; SMN2TP53KMT2A | |
| SCHEMBL27806397 | 0.68 | P2RX4 (0.51) | AHRMAPK1SMN1; SMN2TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |