Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.48 |
| ▸ | CNR2 | P34972 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627696 | 0.76 | LMNA (0.49) | CNR1CNR2TP53RXFP1MEN1 | |
| SCHEMBL16627769 | 0.74 | CNR1 (0.47) | CNR1CNR2MEN1KMT2AF10 | |
| SCHEMBL16627714 | 0.73 | SMN1; SMN2 (0.43) | CNR1CNR2MEN1KMT2AL3MBTL1 | |
| SCHEMBL16627773 | 0.72 | NR2F2 (0.50) | CNR1CNR2MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9356133 | 0.71 | CNR1 (0.54) | CNR1CNR2MEN1KMT2AALDH1A1 | |
| SCHEMBL16236935 | 0.70 | MAOB (0.55) | CNR1CNR2TP53MEN1KMT2A | |
| SCHEMBL16627770 | 0.69 | KMT2A (0.57) | TP53MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL30884510 | 0.69 | CCR2 (0.66) | CNR1CNR2ALDH1A1HPGDLMNA | |
| SCHEMBL11536101 | 0.69 | CCR2 (0.66) | CNR1CNR2ALDH1A1HPGDLMNA | |
| SCHEMBL16627834 | 0.69 | KMT2A (0.53) | CNR1CNR2TP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |