Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 10/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627789 | 0.85 | P2RX7 (0.83) | P2RX7HPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL16627791 | 0.82 | P2RX7 (0.69) | P2RX7NPC1TP53RAB9AP2RX4 | |
| SCHEMBL16627793 | 0.81 | P2RX7 (0.80) | P2RX7HPGDSMN1; SMN2LMNAHTT | |
| SCHEMBL16627790 | 0.80 | P2RX7 (0.70) | P2RX7HPGDKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL16627794 | 0.80 | P2RX7 (0.77) | P2RX7HPGDSMN1; SMN2LMNAHTT | |
| SCHEMBL16627903 | 0.78 | P2RX7 (0.81) | P2RX7TP53P2RX4HDAC1 | |
| SCHEMBL16627901 | 0.76 | P2RX7 (0.78) | P2RX7TP53P2RX4HDAC1 | |
| SCHEMBL16627607 | 0.73 | P2RX7 (0.79) | P2RX7ALDH1A1TP53 | |
| SCHEMBL16627907 | 0.72 | P2RX7 (0.79) | P2RX7KDM4EHSD17B10SMN1; SMN2NPC1 | |
| SCHEMBL16627908 | 0.72 | P2RX7 (0.91) | P2RX7TP53P2RX4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |