Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627714 | 0.91 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4ECNR1CNR2PDE10A | |
| SCHEMBL16627883 | 0.90 | SMN1; SMN2 (0.43) | SMN1; SMN2KDM4ECNR1CNR2PDE10A | |
| SCHEMBL16627881 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2KDM4ECNR1CNR2PDE10A | |
| SCHEMBL16627882 | 0.87 | KMT2A (0.43) | SMN1; SMN2KDM4EHPGDMAPTADORA2A | |
| SCHEMBL16627836 | 0.79 | NR1H2 (0.42) | KDM4ECNR1CNR2NR1H2TP53 | |
| SCHEMBL16627841 | 0.78 | NR1H2 (0.41) | KDM4ECNR1CNR2NR1H2TP53 | |
| SCHEMBL16627837 | 0.78 | NR1H2 (0.41) | KDM4ECNR1CNR2NR1H2TP53 | |
| SCHEMBL16627833 | 0.78 | TDP1 (0.50) | SMN1; SMN2KDM4EALDH1A1LMNAHTT | |
| SCHEMBL16627697 | 0.71 | CNR2 (0.49) | KDM4ECNR1CNR2TP53POLB | |
| SCHEMBL16236935 | 0.70 | MAOB (0.55) | SMN1; SMN2KDM4ECNR1CNR2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |