Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627714 | 0.88 | SMN1; SMN2 (0.43) | KMT2AMEN1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL16627884 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2ADORA2AHPGDMAPTKDM4E | |
| SCHEMBL16627881 | 0.87 | SMN1; SMN2 (0.50) | KMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL16627883 | 0.87 | SMN1; SMN2 (0.43) | SMN1; SMN2RXFP1MAPTKDM4E | |
| SCHEMBL16627836 | 0.76 | NR1H2 (0.42) | KMT2AMEN1MAPTKDM4E | |
| SCHEMBL16627769 | 0.76 | CNR1 (0.47) | KMT2AMEN1SMN1; SMN2ADORA2APPARG | |
| SCHEMBL16627841 | 0.75 | NR1H2 (0.41) | KMT2AMEN1GAAMAPTKDM4E | |
| SCHEMBL16627837 | 0.75 | NR1H2 (0.41) | KMT2AMEN1MAPTKDM4E | |
| SCHEMBL16627833 | 0.75 | TDP1 (0.50) | KMT2AMEN1SMN1; SMN2RXFP1KDM4E | |
| SCHEMBL16627771 | 0.75 | SMN1; SMN2 (0.45) | KMT2AMEN1SMN1; SMN2ADORA2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |