Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627678 | 0.92 | PARP14 (0.52) | PARP14KDM4EMEN1KMT2AMAPT | |
| SCHEMBL16627690 | 0.88 | RXFP1 (0.40) | PARP14KDM4EMEN1KMT2AMAPT | |
| SCHEMBL16627806 | 0.82 | NHERF1 (0.49) | KDM4EMEN1KMT2AMAPTGAA | |
| SCHEMBL16627760 | 0.81 | CCNA2 (0.45) | PARP14KDM4EMEN1KMT2AGAA | |
| SCHEMBL16627890 | 0.80 | PARP14 (0.56) | PARP14KDM4EMEN1KMT2AMAPT | |
| SCHEMBL16627825 | 0.80 | KMT2A (0.53) | PARP14KDM4EKMT2AMAPTGAA | |
| SCHEMBL16627824 | 0.79 | MEN1 (0.47) | KDM4EMEN1KMT2AMAPTGAA | |
| SCHEMBL16627710 | 0.79 | KMT2A (0.52) | PARP14KDM4EMEN1KMT2AMAPT | |
| SCHEMBL16627592 | 0.79 | MT-CO2 (0.44) | PARP14KDM4EMEN1KMT2AGAA | |
| SCHEMBL16627823 | 0.78 | NPY5R (0.47) | KDM4EMEN1KMT2AMAPTNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050379-A1 | NOVEL QUINOLINONE DERIVATIVE AND USE THEREOF | 광주과학기술원 | 2015-04-09 | — | — | WO | disclosed |