Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 7/20 | 0.37 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7802721 | 0.79 | PTPN1 (0.37) | PTPN1CA2CA1SMN1; SMN2PDE4B | |
| SCHEMBL17120591 | 0.79 | DDB1 (0.49) | — | |
| SCHEMBL1755976 | 0.78 | HSD11B1 (0.41) | PTPN1MEN1KMT2APDE4B | |
| SCHEMBL13733238 | 0.78 | MAPT (0.43) | POLBSMN1; SMN2MAPTPTGS1 | |
| SCHEMBL12831493 | 0.77 | PTPN1 (0.39) | PTPN1CA2CA1CA12CA9 | |
| SCHEMBL16628451 | 0.77 | PTPN1 (0.35) | PTPN1PDE4B | |
| SCHEMBL5166212 | 0.77 | PTPN1 (0.38) | PTPN1MEN1KMT2APDE4B | |
| SCHEMBL2780758 | 0.77 | L3MBTL1 (0.42) | PTPN1 | |
| SCHEMBL16628341 | 0.76 | HPGD (0.38) | PTPN1MAPTPDE4B | |
| SCHEMBL10080332 | 0.76 | PDE4B (0.42) | PTPN1POLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2860177-A2 | Synthesis of functionalized arenes | Bayer Intellectual Property GmbH (DE) | 2015-04-15 | — | — | EP | claimed |
| EP-2860177-A2 | Synthesis of functionalized arenes | Bayer Intellectual Property GmbH (DE) | 2015-04-15 | — | — | EP | disclosed |
| EP-2860177-A2 | Synthesis of functionalized arenes | Bayer Intellectual Property GmbH (DE) | 2015-04-15 | — | — | EP | disclosed |