Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12831493 | 0.82 | PTPN1 (0.39) | PTPN1RAB9ANPC1PDE4BHSD11B1 | |
| SCHEMBL7802721 | 0.81 | PTPN1 (0.37) | HPGDPTPN1ALDH1A1PDE4BHSD11B1 | |
| SCHEMBL10058951 | 0.81 | HPGD (0.36) | HPGDPTPN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL1755976 | 0.80 | HSD11B1 (0.41) | PTPN1RAB9ANPC1PDE4BHSD11B1 | |
| SCHEMBL13946932 | 0.80 | SMN1; SMN2 (0.40) | HPGDALDH1A1RAB9ANPC1HSD11B1 | |
| SCHEMBL2780758 | 0.79 | L3MBTL1 (0.42) | PTPN1 | |
| SCHEMBL5166212 | 0.79 | PTPN1 (0.38) | PTPN1PDE4BHSD11B1DHFR | |
| SCHEMBL14901006 | 0.77 | PTPN1 (0.38) | HPGDPTPN1RAB9ANPC1PDE4B | |
| SCHEMBL2060182 | 0.77 | DHFR (0.35) | PTPN1PDE4BHSD11B1DHFR | |
| SCHEMBL16628380 | 0.76 | PTPN1 (0.39) | PTPN1PDE4BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2860177-A2 | Synthesis of functionalized arenes | Bayer Intellectual Property GmbH (DE) | 2015-04-15 | — | — | EP | claimed |
| EP-2860177-A2 | Synthesis of functionalized arenes | Bayer Intellectual Property GmbH (DE) | 2015-04-15 | — | — | EP | disclosed |
| EP-2860177-A2 | Synthesis of functionalized arenes | Bayer Intellectual Property GmbH (DE) | 2015-04-15 | — | — | EP | disclosed |