SCHEMBL16628548

SCHEMBL16628548

NC(=O)C(CCc1ccccc1)N1C(=O)C=CC1=O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.50
ALDH1A1 P00352 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
GSK3A P49840 4/20 0.45
GSK3B P49841 4/20 0.45
MGLL Q99685 3/20 0.45
TSHR P16473 1/20 0.43
ANPEP P15144 2/20 0.41
ERAP1 Q9NZ08 2/20 0.41
ERAP2 Q6P179 1/20 0.41
FAAH O00519 1/20 0.41
DNMT1 P26358 1/20 0.40
CNR2 P34972 1/20 0.40
ADA P00813 2/20 0.39
EPHX1 P07099 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1824376 0.87 DNMT1 (0.48) POLBALDH1A1GSK3AGSK3BMGLL
SCHEMBL31031923 0.76 ALDH1A1 (0.36) POLBALDH1A1L3MBTL1DNMT1
SCHEMBL11024319 0.76 GSK3A (0.53) POLBGSK3AGSK3BMGLLTSHR
SCHEMBL22435 0.76 ALDH1A1 (0.44) POLBALDH1A1GSK3AGSK3BMGLL
SCHEMBL31723987 0.73 KMT2A (0.36) POLBALDH1A1L3MBTL1DNMT1KMT2A
SCHEMBL10536673 0.73 ALDH1A1 (0.68) POLBALDH1A1L3MBTL1TSHRDNMT1
SCHEMBL9326774 0.73 ALDH1A1 (0.68) POLBALDH1A1L3MBTL1TSHRDNMT1
SCHEMBL8873673 0.73 ALDH1A1 (0.68) POLBALDH1A1L3MBTL1TSHRDNMT1
SCHEMBL31723981 0.72 MEN1 (0.35) POLBALDH1A1L3MBTL1DNMT1KMT2A
SCHEMBL2219783 0.72 CA2 (0.43) POLBALDH1A1L3MBTL1MGLLFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015055630-A1 COMPOSITIONS FOR TRANSFECTING NUCLEIC ACID MOLECULES INTO EUKARYOTIC CELLS TECHNISCHE UNIVERSITÄT GRAZ (AT) 2015-04-23 WO claimed
EP-2860255-A1 Compositions comprising cationic and neutral lipids for transfecting nucleic acid molecules into eukaryotic cells Technische Universität Graz (AT) 2015-04-15 EP claimed
WO-2015055630-A1 COMPOSITIONS FOR TRANSFECTING NUCLEIC ACID MOLECULES INTO EUKARYOTIC CELLS TECHNISCHE UNIVERSITÄT GRAZ (AT) 2015-04-23 WO disclosed
EP-2860255-A1 Compositions comprising cationic and neutral lipids for transfecting nucleic acid molecules into eukaryotic cells Technische Universität Graz (AT) 2015-04-15 EP disclosed