SCHEMBL16628549

SCHEMBL16628549

CCC(C(N)=O)c1ccccc1N1C(=O)C=CC1=O

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MGLL Q99685 9/20 0.55
▸ FAAH O00519 1/20 0.55
▸ TLR9 Q9NR96 3/20 0.46
▸ ALDH1A1 P00352 4/20 0.41
▸ HSP90AA1 P07900 3/20 0.41
▸ NPSR1 Q6W5P4 3/20 0.41
▸ ATM Q13315 2/20 0.41
▸ TDP1 Q9NUW8 2/20 0.41
▸ PKM P14618 1/20 0.41
▸ CCR6 P51684 1/20 0.41
▸ BCHE P06276 1/20 0.36
▸ KCNQ2 O43526 3/20 0.35
▸ EPHX1 P07099 1/20 0.34
▸ MAPT P10636 1/20 0.34
▸ HTT P42858 2/20 0.33
▸ MITF O75030 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ CACNA1B Q00975 1/20 0.33
▸ APBA1 Q02410 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL487780 0.87 MGLL (0.57) MGLLFAAHTLR9ALDH1A1HSP90AA1
SCHEMBL19994461 0.85 MGLL (0.51) MGLLFAAHTLR9ALDH1A1HSP90AA1
SCHEMBL28411421 0.78 MGLL (0.66) MGLLFAAHTLR9ALDH1A1HSP90AA1
SCHEMBL3875399 0.76 MGLL (0.69) MGLLFAAHTLR9ALDH1A1HSP90AA1
SCHEMBL28876528 0.75 KCNQ2 (0.53) KCNQ2
SCHEMBL8612836 0.73 MGLL (0.55) MGLLFAAHTLR9ALDH1A1HSP90AA1
SCHEMBL2348816 0.73 MGLL (0.53) MGLLFAAHALDH1A1HSP90AA1NPSR1
SCHEMBL5504222 0.73 EPHX1 (0.41) ALDH1A1EPHX1
SCHEMBL2030601 0.73 ALDH1A1 (0.44) ALDH1A1TDP1EPHX1
SCHEMBL10515048 0.73 TSHR (0.55) ALDH1A1EPHX1MAPTHTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015055630-A1 COMPOSITIONS FOR TRANSFECTING NUCLEIC ACID MOLECULES INTO EUKARYOTIC CELLS TECHNISCHE UNIVERSITÄT GRAZ (AT) 2015-04-23 — — WO claimed
EP-2860255-A1 Compositions comprising cationic and neutral lipids for transfecting nucleic acid molecules into eukaryotic cells Technische Universität Graz (AT) 2015-04-15 — — EP claimed
US-20220088215-A1 METHODS OF MAKING TARGETED VESICLES, AND COMPOSITIONS MADE THEREBY UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2022-03-24 — — US disclosed
EP-3946269-A1 METHODS OF MAKING TARGETED VESICLES, AND COMPOSITIONS MADE THEREBY University of Georgia Research Foundation, Inc. (US) 2022-02-09 — — EP disclosed
WO-2020198626-A1 METHODS OF MAKING TARGETED VESICLES, AND COMPOSITIONS MADE THEREBY UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2020-10-01 — — WO disclosed
WO-2015055630-A1 COMPOSITIONS FOR TRANSFECTING NUCLEIC ACID MOLECULES INTO EUKARYOTIC CELLS TECHNISCHE UNIVERSITÄT GRAZ (AT) 2015-04-23 — — WO disclosed
EP-2860255-A1 Compositions comprising cationic and neutral lipids for transfecting nucleic acid molecules into eukaryotic cells Technische Universität Graz (AT) 2015-04-15 — — EP disclosed
Send feedback