Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.57 |
| ▸ | FAAH | O00519 | 1/20 | 0.57 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16628549 | 0.87 | MGLL (0.55) | MGLLFAAHTLR9ALDH1A1HSP90AA1 | |
| SCHEMBL28794436 | 0.84 | PPARG (0.46) | ALDH1A1HTR1AADRA1AKCNQ2 | |
| SCHEMBL19994461 | 0.83 | MGLL (0.51) | MGLLFAAHTLR9ALDH1A1HSP90AA1 | |
| SCHEMBL28411421 | 0.82 | MGLL (0.66) | MGLLFAAHTLR9ALDH1A1HSP90AA1 | |
| SCHEMBL8612836 | 0.78 | MGLL (0.55) | MGLLFAAHTLR9ALDH1A1HSP90AA1 | |
| SCHEMBL3875399 | 0.78 | MGLL (0.69) | MGLLFAAHTLR9ALDH1A1HSP90AA1 | |
| SCHEMBL29707903 | 0.73 | MGLL (1.00) | MGLLFAAHTLR9ALDH1A1HSP90AA1 | |
| SCHEMBL3482778 | 0.73 | MGLL (1.00) | MGLLFAAHTLR9ALDH1A1HSP90AA1 | |
| SCHEMBL3414901 | 0.72 | MGLL (0.54) | MGLLFAAHALDH1A1HSP90AA1NPSR1 | |
| SCHEMBL6773227 | 0.72 | TSHR (0.57) | ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2410991-A1 | ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS | SDG, INC. (an Ohio Corporation ) (US) | 2012-02-01 | — | — | EP | claimed |
| EP-0968223-B1 | BIOCONJUGATION OF MACROMOLECULES | SIGMA ALDRICH CO LLC (US) | 2016-12-21 | — | — | EP | disclosed |
| EP-2256133-B1 | Bioconjugation of macromolecules | SIGMA ALDRICH CO LLC (US) | 2016-12-14 | — | — | EP | disclosed |
| EP-2319854-B1 | Bioconjugation Of Macromolecules | SIGMA ALDRICH CO LLC (US) | 2016-11-30 | — | — | EP | disclosed |
| EP-2319855-B1 | Bioconjugation of Macromolecules | SIGMA ALDRICH CO LLC (US) | 2016-04-06 | — | — | EP | disclosed |
| WO-2011041003-A9 | COMPOSITIONS AND METHODS FOR PREPARING STAPHYLOCOCCUS AUREUS SEROTYPE 5 AND 8 CAPSULAR POLYSACCHARIDE CONJUGATE IMMUNOGENIC COMPOSITIONS | WYETH LLC (US) | 2011-06-09 | — | — | WO | disclosed |
| EP-2319855-A1 | Bioconjugation of Macromolecules | Sigma-Aldrich Co. (US) | 2011-05-11 | — | — | EP | disclosed |
| EP-2319854-A1 | Bioconjugation Of Macromolecules | Sigma-Aldrich Co. (US) | 2011-05-11 | — | — | EP | disclosed |
| WO-2011041003-A2 | COMPOSITIONS AND METHODS FOR PREPARING STAPHYLOCOCCUS AUREUS SEROTYPE 5 AND 8 CAPSULAR POLYSACCHARIDE CONJUGATE IMMUNOGENIC COMPOSITIONS | WYETH LLC (US) | 2011-04-07 | — | — | WO | disclosed |
| EP-2256133-A1 | Bioconjugation of macromolecules | Sigma-Aldrich Co. (US) | 2010-12-01 | — | — | EP | disclosed |
| WO-1999013919-A1 | NOVEL TARGETED CONTRAST AGENTS FOR DIAGNOSTIC AND THERAPEUTIC USE | IMARX PHARMACEUTICAL CORP. (US) | 1999-03-25 | — | — | WO | disclosed |
| WO-1998030575-A1 | BIOCONJUGATION OF MACROMOLECULES | PROLIGO LLC (US) | 1998-07-16 | — | — | WO | disclosed |
| EP-0833613-A1 | DELIVERY VEHICLES COMPRISING STABLE LIPID/NUCLEIC ACID COMPLEXES | SOMATIX THERAPY CORPORATION (US) | 1998-04-08 | — | — | EP | disclosed |
| EP-0831932-A1 | NOVEL TARGETED COMPOSITIONS FOR DIAGNOSTIC AND THERAPEUTIC USE | IMARX PHARMACEUTICAL CORP. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1997045069-A9 | CATIONIC POLYMER/LIPID NUCLEIC ACID DELIVERY VEHICLES | — | 1998-03-26 | — | — | WO | disclosed |
| WO-1997045069-A1 | CATIONIC POLYMER/LIPID NUCLEIC ACID DELIVERY VEHICLES | CELL GENESYS, INC. (US) | 1997-12-04 | — | — | WO | disclosed |
| EP-0434317-B1 | Immunoadsorbents | CROSFIELD JOSEPH & SONS (GB) | 1997-03-05 | — | — | EP | disclosed |
| WO-1996040285-A1 | NOVEL TARGETED COMPOSITIONS FOR DIAGNOSTIC AND THERAPEUTIC USE | IMARX PHARMACEUTICAL CORP. (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996037194-A1 | DELIVERY VEHICLES COMPRISING STABLE LIPID/NUCLEIC ACID COMPLEXES | SOMATIX THERAPY CORPORATION (US) | 1996-11-28 | — | — | WO | disclosed |
| EP-0434317-A1 | Immunoadsorbents | CROSFIELD LIMITED (GB) | 1991-06-26 | — | — | EP | disclosed |