Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 15/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 6/20 | 0.47 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3414901 | 0.86 | MGLL (0.54) | MGLLNPSR1HSP90AA1ALDH1A1HPGD | |
| SCHEMBL24452742 | 0.79 | MGLL (0.62) | MGLLNPSR1HSP90AA1ALDH1A1HPGD | |
| SCHEMBL2125273 | 0.78 | ALDH1A1 (0.46) | MGLLNPSR1HSP90AA1ALDH1A1HPGD | |
| SCHEMBL7633213 | 0.76 | MGLL (0.63) | MGLLNPSR1HSP90AA1ALDH1A1HPGD | |
| SCHEMBL19134296 | 0.75 | MGLL (0.67) | MGLLNPSR1HSP90AA1ALDH1A1HPGD | |
| SCHEMBL2267506 | 0.75 | HSP90AA1 (0.42) | MGLLNPSR1HSP90AA1ALDH1A1HPGD | |
| SCHEMBL4943215 | 0.74 | LMNA (0.54) | TDP1LMNAMAPTADRA1A | |
| SCHEMBL26898446 | 0.74 | ALDH1A1 (0.50) | ALDH1A1TDP1LMNAMEN1KMT2A | |
| SCHEMBL28234925 | 0.74 | CRHBP (0.53) | HTTMAPK1LMNA | |
| SCHEMBL2290009 | 0.74 | EPHX1 (0.43) | ALDH1A1HTTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4021475-A1 | PEPTIDE INHIBITORS OF FOCAL ADHESION KINASE ACTIVITY AND USES THEREOF | Arizona Board of Regents on behalf of the University of Arizona (US) | 2022-07-06 | — | — | EP | claimed |
| EP-4408480-A1 | COMPOSITIONS AND METHODS FOR METAL CONTAINING FORMULATIONS CAPABLE OF MODULATING IMMUNE RESPONSE | The Regents Of The University Of Michigan (US) | 2024-08-07 | — | — | EP | disclosed |
| EP-4359004-A1 | COMPOSITIONS AND METHODS FOR INCREASING THE EFFICACY OF IMMUNOTHERAPIES AND VACCINES | The Regents Of The University Of Michigan (US) | 2024-05-01 | — | — | EP | disclosed |
| WO-2023056427-A1 | COMPOSITIONS AND METHODS FOR METAL CONTAINING FORMULATIONS CAPABLE OF MODULATING IMMUNE RESPONSE | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2023-04-06 | — | — | WO | disclosed |
| WO-2022271822-A1 | COMPOSITIONS AND METHODS FOR INCREASING THE EFFICACY OF IMMUNOTHERAPIES AND VACCINES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2022-12-29 | — | — | WO | disclosed |
| EP-2830991-A1 | LIPID-COATED NUCLEIC ACID NANOSTRUCTURES OF DEFINED SHAPE | President and Fellows of Harvard College (US) | 2015-02-04 | — | — | EP | disclosed |
| WO-2013148186-A1 | LIPID-COATED NUCLEIC ACID NANOSTRUCTURES OF DEFINED SHAPE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2013-10-03 | — | — | WO | disclosed |
| US-8003078-B2 | Targeted MR imaging agents | BARNES-JEWISH HOSPITAL (US) | 2011-08-23 | — | — | US | disclosed |
| EP-1539252-A4 | BLOOD CLOT-TARGETED NANOPARTICLES | BARNES JEWISH HOSPITAL (US) | 2008-03-12 | — | — | EP | disclosed |
| US-20070237721-A1 | TARGETED MR IMAGING AGENTS | KEREOS, INC. | 2007-10-11 | — | — | US | disclosed |
| EP-1539252-A2 | BLOOD CLOT-TARGETED NANOPARTICLES | Barnes-Jewish Hospital (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004017907-A2 | BLOOD CLOT-TARGETED NANOPARTICLES | BARNES-JEWISH HOSPITAL (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070237721-A1 | TARGETED MR IMAGING AGENTS | TSPO, ARNT, RXFP4 | MGLL 1683/4885NPSR1 908/4885HSP90AA1 1548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.