Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8311559 | 0.83 | OPRM1 (0.49) | SMN1; SMN2POLBHSD11B1PPIDMEN1 | |
| SCHEMBL2636117 | 0.82 | SMN1; SMN2 (0.46) | SMN1; SMN2POLBHSD11B1PPIDMEN1 | |
| SCHEMBL988620 | 0.81 | POLB (0.47) | SMN1; SMN2POLBHSD11B1PPIDMEN1 | |
| SCHEMBL28137288 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBHSD11B1PPIDMEN1 | |
| SCHEMBL28100629 | 0.78 | HSD11B1 (0.50) | SMN1; SMN2POLBHSD11B1PPIDMEN1 | |
| SCHEMBL9734283 | 0.78 | CCR1 (0.47) | SMN1; SMN2POLBHSD11B1PPIDMEN1 | |
| SCHEMBL11847067 | 0.76 | SMN1; SMN2 (0.47) | SMN1; SMN2POLBHSD11B1PPIDMEN1 | |
| SCHEMBL5972813 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2POLBHSD11B1PPIDMEN1 | |
| SCHEMBL27309743 | 0.76 | PIN1 (0.46) | SMN1; SMN2POLBHSD11B1PPIDMEN1 | |
| SCHEMBL27811397 | 0.75 | POLB (0.47) | SMN1; SMN2POLBHSD11B1PPIDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049168-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-09 | — | — | WO | disclosed |