Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.33 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21278147 | 0.90 | CETP (0.34) | CETPGPR119HTT | |
| SCHEMBL18017461 | 0.89 | CETP (0.34) | CETPMEN1KMT2AGPR119LIMK2 | |
| SCHEMBL16630218 | 0.88 | CETP (0.37) | CETPMEN1KMT2AGPR119LIMK2 | |
| SCHEMBL16629828 | 0.85 | CETP (0.38) | CETPMEN1KMT2AGPR119LIMK2 | |
| SCHEMBL16629823 | 0.84 | CETP (0.36) | CETPMEN1KMT2AGPR119LIMK2 | |
| SCHEMBL18210813 | 0.84 | CYP3A4 (0.33) | CETPGPR119HTT | |
| SCHEMBL16629855 | 0.84 | GPR119 (0.42) | CETPMEN1KMT2AGPR119LIMK2 | |
| SCHEMBL21278650 | 0.82 | GPR119 (0.41) | CETPGPR119LIMK2USP30 | |
| SCHEMBL16629852 | 0.81 | CETP (0.32) | CETP | |
| SCHEMBL18017450 | 0.81 | GPR119 (0.36) | CETPMEN1KMT2AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050798-A1 | NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2015-04-09 | — | — | WO | disclosed |