Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 13/20 | 0.56 |
| ▸ | RBP4 | P02753 | 1/20 | 0.53 |
| ▸ | CYBB | P04839 | 1/20 | 0.50 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.50 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7535800 | 0.86 | SMARCA2 (0.49) | P2RX7MAPK1 | |
| SCHEMBL3653185 | 0.86 | P2RX7 (0.55) | P2RX7MAPK1 | |
| SCHEMBL2604326 | 0.85 | PDE4B (0.44) | P2RX7CYBBNOX5NOX4NOX1 | |
| SCHEMBL1583488 | 0.85 | MEN1 (0.51) | P2RX7MEN1KMT2AMAPK1 | |
| SCHEMBL30734152 | 0.85 | MEN1 (0.51) | P2RX7MEN1KMT2AMAPK1 | |
| SCHEMBL2889100 | 0.83 | MEN1 (0.45) | P2RX7RBP4CYBBNOX5NOX4 | |
| SCHEMBL2604325 | 0.83 | MAPK1 (0.44) | P2RX7MAPK1POLB | |
| SCHEMBL30208139 | 0.83 | MEN1 (0.56) | MEN1KMT2APOLB | |
| SCHEMBL14852499 | 0.83 | MEN1 (0.56) | MEN1KMT2APOLB | |
| SCHEMBL1662873 | 0.82 | P2RX7 (0.47) | P2RX7RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |