Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 13/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | RBP4 | P02753 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1584703 | 0.87 | CPS1 (0.46) | P2RX7KDM4EMAPTALDH1A1STS | |
| SCHEMBL1663013 | 0.82 | P2RX7 (0.56) | P2RX7RBP4 | |
| SCHEMBL1665532 | 0.81 | ALDH1A1 (0.53) | KDM4EMAPTALDH1A1STSNR1H2 | |
| SCHEMBL31342592 | 0.78 | SUV39H2 (0.44) | P2RX7MAPTALDH1A1RBP4ESR2 | |
| SCHEMBL2366725 | 0.77 | NR1H2 (0.44) | P2RX7MAPTALDH1A1ESR2NR1H2 | |
| SCHEMBL1662799 | 0.76 | NR1H2 (0.41) | P2RX7KDM4EMAPTALDH1A1RBP4 | |
| SCHEMBL1583767 | 0.76 | GPR119 (0.46) | KDM4EMAPTALDH1A1NR1H2 | |
| SCHEMBL4537183 | 0.76 | P2RX7 (0.55) | P2RX7 | |
| SCHEMBL22650493 | 0.75 | NR1H2 (0.54) | P2RX7ESR2NR1H2 | |
| SCHEMBL1662960 | 0.75 | P2RX7 (0.44) | P2RX7MAPTESR2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |