Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 14/20 | 0.53 |
| ▸ | RBP4 | P02753 | 1/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3653187 | 0.87 | P2RX7 (0.52) | P2RX7P2RX4ALDH1A1MAPTTSHR | |
| SCHEMBL1583489 | 0.86 | SCN9A (0.51) | P2RX7P2RX4ALDH1A1MAPTTSHR | |
| SCHEMBL3651536 | 0.80 | P2RX7 (0.63) | P2RX7ALDH1A1MAPT | |
| SCHEMBL1663013 | 0.80 | P2RX7 (0.56) | P2RX7RBP4 | |
| SCHEMBL1583149 | 0.78 | DPP4 (0.49) | ALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL1583384 | 0.77 | KDM4E (0.48) | P2RX7ALDH1A1MAPTKIT | |
| SCHEMBL1583909 | 0.77 | HSD17B10 (0.41) | P2RX4ALDH1A1TSHRHSD17B10KIT | |
| SCHEMBL3654102 | 0.76 | P2RX7 (0.51) | P2RX7ALDH1A1HSD17B10KIT | |
| SCHEMBL1662961 | 0.76 | P2RX7 (0.42) | P2RX7ALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL1583153 | 0.76 | ROCK2 (0.50) | ALDH1A1TSHRKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |