Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18017468 | 0.90 | — | — | |
| SCHEMBL16629834 | 0.89 | AGTR2 (0.36) | GPR119CETP | |
| SCHEMBL21278147 | 0.84 | CETP (0.34) | GPR119CETP | |
| SCHEMBL18017457 | 0.82 | MAPK14 (0.39) | GPR119CETP | |
| SCHEMBL16620038 | 0.81 | ADRB1 (0.38) | GPR119CETP | |
| SCHEMBL18017379 | 0.81 | ADRB1 (0.38) | GPR119CETP | |
| SCHEMBL16620041 | 0.81 | ADRB1 (0.38) | GPR119CETP | |
| SCHEMBL16619851 | 0.79 | ADRB3 (0.38) | — | |
| SCHEMBL16619853 | 0.79 | ADRB3 (0.38) | — | |
| SCHEMBL21278412 | 0.79 | GPR119 (0.36) | GPR119CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050798-A1 | NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2015-04-09 | — | — | WO | disclosed |