Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.35 |
| ▸ | CETP | P11597 | 4/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21278147 | 0.92 | CETP (0.34) | AGTR2GPR119CETP | |
| SCHEMBL16630760 | 0.89 | GPR119 (0.31) | GPR119CETP | |
| SCHEMBL18017452 | 0.88 | AGTR2 (0.33) | AGTR2GPR119CETP | |
| SCHEMBL16620041 | 0.88 | ADRB1 (0.38) | GPR119CETPCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL18017379 | 0.88 | ADRB1 (0.38) | GPR119CETPCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL16620038 | 0.88 | ADRB1 (0.38) | GPR119CETPCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL21278412 | 0.87 | GPR119 (0.36) | GPR119CETPCHRNB2CHRNA7CHRNA4 | |
| SCHEMBL18017457 | 0.86 | MAPK14 (0.39) | GPR119CETPCHRNB2CHRNA4 | |
| SCHEMBL16629887 | 0.85 | GPR119 (0.37) | GPR119CETPKMT2A | |
| SCHEMBL18210822 | 0.85 | ACKR3 (0.38) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050798-A1 | NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2015-04-09 | — | — | WO | disclosed |