Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.56 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.53 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2302446 | 0.86 | FFAR4 (0.46) | FFAR1AKR1B1FFAR4GSTP1NR4A2 | |
| SCHEMBL418611 | 0.85 | GPR52 (0.50) | FFAR1AKR1B1FFAR4NR4A2 | |
| SCHEMBL13680783 | 0.84 | FFAR1 (0.45) | FFAR1AKR1B1FFAR4GSTP1PTGER4 | |
| SCHEMBL18383719 | 0.84 | CYP4F2 (0.64) | FFAR1NR4A2MAOAMAOBLCK | |
| SCHEMBL2772725 | 0.84 | FFAR1 (0.61) | FFAR1FFAR4NR4A2MAOAMAOB | |
| SCHEMBL11464931 | 0.82 | FFAR1 (0.59) | FFAR1FFAR4NR4A2MAOAMAOB | |
| SCHEMBL13680784 | 0.81 | ABL1 (0.50) | FFAR1PPARDMAOB | |
| SCHEMBL18165304 | 0.81 | FFAR1 (0.85) | FFAR1AKR1B1FFAR4PTGER4PTGER3 | |
| SCHEMBL2807881 | 0.80 | MAOA (0.70) | FFAR1AKR1B1FFAR4GSTP1PTGER4 | |
| SCHEMBL16346074 | 0.79 | GSTP1 (0.66) | FFAR1AKR1B1FFAR4GSTP1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051045-A2 | 3'END CAPS FOR RNAi AGENTS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |