Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631060 | 0.84 | FFAR1 (0.56) | FFAR1FFAR4AKR1B1PTGER4PTGER3 | |
| SCHEMBL13680784 | 0.82 | ABL1 (0.50) | FFAR1GPR52 | |
| SCHEMBL2302446 | 0.81 | FFAR4 (0.46) | FFAR1FFAR4AKR1B1GSTP1GPR52 | |
| SCHEMBL13680791 | 0.81 | GAA (0.55) | FFAR1FFAR4AKR1B1GPR52 | |
| SCHEMBL13680792 | 0.81 | MEN1 (0.42) | FFAR1FFAR4AKR1B1F2ACMSD | |
| SCHEMBL418611 | 0.80 | GPR52 (0.50) | FFAR1FFAR4AKR1B1ACMSDGPR52 | |
| SCHEMBL13680786 | 0.79 | CHRM2 (0.46) | — | |
| SCHEMBL8367734 | 0.79 | DRD1 (0.52) | PTGER4 | |
| SCHEMBL13681368 | 0.79 | AOC3 (0.40) | FFAR1FFAR4AKR1B1GPR52 | |
| SCHEMBL13680799 | 0.78 | ACHE (0.52) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |