Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 10/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | HBB | P68871 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631406 | 0.86 | LMNA (0.56) | LMNAADORA3PMP22HBBMAPT | |
| SCHEMBL23098378 | 0.78 | ADK (0.56) | ADKLMNAADORA3PMP22HBB | |
| SCHEMBL28350236 | 0.77 | ADK (0.41) | ADKLMNAADORA3PMP22HBB | |
| SCHEMBL19657131 | 0.77 | LMNA (0.56) | ADKLMNAADORA3PMP22HBB | |
| SCHEMBL10013535 | 0.77 | LMNA (0.56) | ADKLMNAADORA3PMP22HBB | |
| SCHEMBL3825501 | 0.77 | ADK (0.57) | ADKLMNAADORA3PMP22HBB | |
| SCHEMBL15119375 | 0.77 | LMNA (0.56) | ADKLMNAADORA3PMP22HBB | |
| SCHEMBL2467656 | 0.77 | LMNA (0.56) | ADKLMNAADORA3PMP22HBB | |
| SCHEMBL3827614 | 0.77 | ADK (0.57) | ADKLMNAADORA3PMP22HBB | |
| SCHEMBL331945 | 0.77 | LMNA (0.56) | ADKLMNAADORA3PMP22HBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |