Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HBB | P68871 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.44 |
| ▸ | TK2 | O00142 | 2/20 | 0.42 |
| ▸ | TK1 | P04183 | 1/20 | 0.42 |
| ▸ | ADK | P55263 | 5/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631494 | 0.86 | P2RY2 (0.54) | P2RY2TK2TK1ADORA3 | |
| SCHEMBL16631635 | 0.82 | TSHR (0.52) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL18080029 | 0.78 | P2RY2 (0.60) | P2RY2 | |
| SCHEMBL16631321 | 0.74 | BCHE (0.50) | TSHRLMNATK2TK1BCHE | |
| SCHEMBL16631203 | 0.74 | TSHR (0.49) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL18080388 | 0.72 | BCHE (0.47) | TSHRLMNABCHEABCB1ABCG2 | |
| SCHEMBL16631370 | 0.71 | ADORA3 (0.53) | P2RY2TK2TK1ADORA3 | |
| SCHEMBL6909337 | 0.70 | LMNA (0.72) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL10323532 | 0.70 | LMNA (0.72) | TSHRLMNAMAPTPMP22HBB | |
| SCHEMBL16774561 | 0.70 | LMNA (0.72) | TSHRLMNAMAPTPMP22HBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |