SCHEMBL16631405

SCHEMBL16631405

CCc1ccc(-c2cccc(CC(C)C)c2)cc1-c1ccccn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSS P25774 2/20 0.41
CTSK P43235 2/20 0.41
GRM5 P41594 2/20 0.41
CTSL P07711 2/20 0.41
CTSB P07858 1/20 0.41
HRH3 Q9Y5N1 1/20 0.38
PTGS2 P35354 1/20 0.37
TRPM8 Q7Z2W7 2/20 0.37
F2 P00734 1/20 0.37
F10 P00742 1/20 0.37
PRSS1 P07477 1/20 0.37
NMT1 P30419 1/20 0.36
FFAR1 O14842 1/20 0.35
HIF1A Q16665 1/20 0.35
PPARG P37231 2/20 0.35
PPARD Q03181 1/20 0.35
PPARA Q07869 1/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17234377 0.85 CTSS (0.40) CTSSCTSKGRM5CTSLCTSB
SCHEMBL19026507 0.84 PDCD1 (0.40) CTSSCTSKPTGS2
SCHEMBL649582 0.82 HRH3 (0.50) CTSSCTSKCTSLCTSBHRH3
SCHEMBL12435670 0.81 HRH3 (0.52) CTSSCTSKCTSLCTSBHRH3
SCHEMBL18019469 0.81 CTSS (0.40) CTSSCTSKCTSLCTSBHRH3
SCHEMBL15137740 0.81 GRM5 (0.48) GRM5HIF1ACYP1A2CYP2D6CYP19A1
SCHEMBL16870991 0.80 CTSS (0.37) CTSSCTSKCTSLCTSBHRH3
SCHEMBL16631453 0.79 TGFBR1 (0.40) CTSKGRM5CTSLTRPM8HIF1A
SCHEMBL15748491 0.75 CTSK (0.41) CTSSCTSKNMT1PPARA
SCHEMBL18790906 0.73 ASIC3 (0.44) CTSSCTSKCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732099-B1 Organic electroluminescent compounds and organic electroluminescent devices comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-08-15 US disclosed
WO-2015050391-A1 AN ORGANIC ELECTROLUMINESCENT COMPOUND AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2015-04-09 WO disclosed