Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | ADK | P55263 | 11/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631358 | 0.85 | LMNA (0.48) | LMNAMAPTPMP22HBBSMN1; SMN2 | |
| SCHEMBL16631504 | 0.84 | LMNA (0.44) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL16631656 | 0.79 | LMNA (0.53) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL16631886 | 0.78 | LMNA (0.49) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL16631355 | 0.76 | LMNA (0.52) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL18080281 | 0.75 | P2RY2 (0.59) | — | |
| SCHEMBL16631376 | 0.75 | LMNA (0.51) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL16631486 | 0.75 | PYGM (0.43) | LMNAMAPTPMP22HBB | |
| SCHEMBL16631877 | 0.74 | LMNA (0.46) | LMNATSHRMAPTPMP22HBB | |
| SCHEMBL16631667 | 0.74 | LMNA (0.49) | LMNATSHRMAPTPMP22HBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |