Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ADK | P55263 | 9/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631419 | 0.85 | LMNA (0.46) | LMNAMAPTPMP22HBBSMN1; SMN2 | |
| SCHEMBL16631421 | 0.84 | LMNA (0.44) | LMNAMAPTTSHRPMP22HBB | |
| SCHEMBL16631656 | 0.78 | LMNA (0.53) | LMNAMAPTTSHRPMP22HBB | |
| SCHEMBL16631886 | 0.77 | LMNA (0.49) | LMNAMAPTTSHRPMP22HBB | |
| SCHEMBL18080286 | 0.76 | P2RY2 (0.55) | — | |
| SCHEMBL16631636 | 0.76 | PYGM (0.41) | LMNAMAPTPMP22HBBSMN1; SMN2 | |
| SCHEMBL16631355 | 0.75 | LMNA (0.52) | LMNAMAPTTSHRPMP22HBB | |
| SCHEMBL18081878 | 0.75 | P2RY6 (0.33) | — | |
| SCHEMBL16631376 | 0.74 | LMNA (0.51) | LMNAMAPTTSHRPMP22HBB | |
| SCHEMBL16631667 | 0.73 | LMNA (0.49) | LMNAMAPTTSHRPMP22HBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |