Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631707 | 0.88 | KMT2A (0.31) | MAPTKMT2ARXFP1 | |
| SCHEMBL16631922 | 0.86 | L3MBTL1 (0.35) | L3MBTL1MAPTKMT2ARXFP1KDM4E | |
| SCHEMBL16631912 | 0.84 | HSP90AA1 (0.33) | HSP90AA1SLC9A1 | |
| SCHEMBL18080508 | 0.77 | L3MBTL1 (0.30) | L3MBTL1 | |
| SCHEMBL16631746 | 0.73 | MAP4K1 (0.32) | HSP90AA1SLC9A1 | |
| SCHEMBL16631553 | 0.73 | KMT2A (0.33) | KMT2A | |
| SCHEMBL16631679 | 0.72 | KDM4E (0.38) | KDM4E | |
| SCHEMBL18081958 | 0.72 | JAK1 (0.30) | SLC9A1 | |
| SCHEMBL16631938 | 0.71 | KMT2A (0.36) | MAPTKMT2ARXFP1KDM4E | |
| SCHEMBL18081969 | 0.70 | L3MBTL1 (0.33) | L3MBTL1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |