SCHEMBL16631553

SCHEMBL16631553

CCc1cc2c(C)c(C)c[nH]c-2nc1=S

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16631496 0.83
SCHEMBL16631922 0.76 L3MBTL1 (0.35) KMT2A
SCHEMBL18080487 0.75 LMNA (0.30)
SCHEMBL16631527 0.73 KMT2A (0.33) KMT2A
SCHEMBL16631452 0.73 L3MBTL1 (0.33) KMT2A
SCHEMBL16631707 0.73 KMT2A (0.31) KMT2A
SCHEMBL16631439 0.68
SCHEMBL16631416 0.66
SCHEMBL18080450 0.66 LMNA (0.30)
SCHEMBL16631414 0.64 NR1I3 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015051173-A2 POLYNUCLEOTIDE MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC (US) 2015-04-09 WO disclosed