Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631746 | 0.89 | MAP4K1 (0.32) | HSP90AA1SLC9A1HCAR2GRIN2DGRIN3B | |
| SCHEMBL16631452 | 0.84 | L3MBTL1 (0.33) | HSP90AA1SLC9A1 | |
| SCHEMBL18081958 | 0.83 | JAK1 (0.30) | SLC9A1 | |
| SCHEMBL18080470 | 0.78 | TRPV1 (0.32) | — | |
| SCHEMBL16631496 | 0.72 | — | — | |
| SCHEMBL16631430 | 0.72 | KDM4E (0.36) | HCAR2 | |
| SCHEMBL16631707 | 0.72 | KMT2A (0.31) | — | |
| SCHEMBL18081954 | 0.71 | NPC1 (0.33) | SLC9A1 | |
| SCHEMBL18081800 | 0.70 | SLC9A1 (0.30) | SLC9A1 | |
| SCHEMBL16631392 | 0.70 | NPC1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |