Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 11/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631430 | 0.84 | KDM4E (0.36) | KDM4EALDH1A1DGAT1HCAR2CYP1A2 | |
| SCHEMBL18081962 | 0.82 | NOTUM (0.34) | KDM4EALDH1A1DGAT1CYP1A2CYP2C9 | |
| SCHEMBL18080513 | 0.79 | KDM4E (0.32) | KDM4EALDH1A1 | |
| SCHEMBL16631707 | 0.72 | KMT2A (0.31) | — | |
| SCHEMBL16631452 | 0.72 | L3MBTL1 (0.33) | KDM4E | |
| SCHEMBL18081918 | 0.72 | NOTUM (0.35) | KDM4EALDH1A1DGAT1CYP1A2CYP2C9 | |
| SCHEMBL16631922 | 0.70 | L3MBTL1 (0.35) | KDM4EALDH1A1 | |
| SCHEMBL16631684 | 0.70 | KDM4E (0.33) | KDM4EALDH1A1DGAT1 | |
| SCHEMBL16631705 | 0.69 | TNKS (0.33) | KDM4EALDH1A1 | |
| SCHEMBL18080475 | 0.69 | KDM4E (0.33) | KDM4EALDH1A1DGAT1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |