Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | HMBS | P08397 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631527 | 0.82 | KMT2A (0.33) | DAOHMBSMAPTKMT2A | |
| SCHEMBL18081761 | 0.81 | DAO (0.37) | DAOHMBSKDM4E | |
| SCHEMBL18080449 | 0.75 | DAO (0.33) | DAOHMBSKDM4E | |
| SCHEMBL16631462 | 0.73 | SMN1; SMN2 (0.36) | DAOKDM4ETP53ALDH1A1GAA | |
| SCHEMBL16631496 | 0.72 | — | — | |
| SCHEMBL16631471 | 0.70 | MAPK1 (0.37) | KDM4ETP53ALDH1A1GAAMAPT | |
| SCHEMBL18081934 | 0.67 | HMBS (0.37) | HMBS | |
| SCHEMBL15782179 | 0.66 | DAO (0.54) | DAOHMBSKDM4ETP53MEN1 | |
| SCHEMBL16631364 | 0.64 | MGAM (0.35) | TP53ALDH1A1GAA | |
| SCHEMBL16631936 | 0.62 | HIF1A (0.33) | KDM4EALDH1A1MAPTHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |