Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631709 | 0.82 | NR1I3 (0.41) | MAPK1SMN1; SMN2GAAMAPTTP53 | |
| SCHEMBL18081932 | 0.81 | MAPK1 (0.40) | MAPK1SMN1; SMN2GAAMAPTKDM4E | |
| SCHEMBL18080464 | 0.75 | TRPV1 (0.36) | MAPK1SMN1; SMN2GAAMAPTTP53 | |
| SCHEMBL16631462 | 0.73 | SMN1; SMN2 (0.36) | SMN1; SMN2GAAMAPTTP53L3MBTL1 | |
| SCHEMBL16631936 | 0.72 | HIF1A (0.33) | SMN1; SMN2MAPTL3MBTL1KDM4EHSD17B10 | |
| SCHEMBL16631411 | 0.72 | TNKS (0.36) | ADORA1HPGDTMIGD3 | |
| SCHEMBL16631745 | 0.71 | HCAR2 (0.34) | HPGD | |
| SCHEMBL16631495 | 0.70 | DAO (0.34) | SMN1; SMN2GAAMAPTTP53KDM4E | |
| SCHEMBL18081951 | 0.67 | NR1I3 (0.45) | SMN1; SMN2GAAMAPTKDM4EHPGD | |
| SCHEMBL16631746 | 0.65 | MAP4K1 (0.32) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |