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SCHEMBL16631545

SCHEMBL16631545

O=c1[nH]c(=O)n([C@@H]2O[C@H](CO)C(O)[C@@H]2O)cc1Cc1c[nH]nn1

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ PYGM P11217 3/20 0.56
▸ TK2 O00142 2/20 0.53
▸ DNPH1 O43598 1/20 0.53
▸ SLC28A1 O00337 1/20 0.48
▸ SLC28A2 O43868 1/20 0.48
▸ SLC29A1 Q99808 1/20 0.48
▸ SLC28A3 Q9HAS3 1/20 0.48
▸ PAX8 Q06710 1/20 0.45
▸ P2RY2 P41231 5/20 0.45
▸ HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16631517 0.82 PYGM (0.55) PYGMTK2DNPH1SLC28A1SLC28A2
SCHEMBL18080034 0.82 P2RY6 (0.63) DNPH1P2RY2
SCHEMBL16631588 0.82 LMNA (0.50) PAX8
SCHEMBL16631852 0.81 PYGM (0.58) PYGMTK2DNPH1SLC28A1SLC28A2
SCHEMBL16631628 0.81 PYGM (0.53) PYGMTK2DNPH1SLC28A1SLC28A2
SCHEMBL14929135 0.81 DNPH1 (0.71) PYGMTK2DNPH1SLC28A1SLC28A2
SCHEMBL263751 0.81 DNPH1 (0.71) PYGMTK2DNPH1SLC28A1SLC28A2
SCHEMBL14853793 0.81 DNPH1 (0.71) PYGMTK2DNPH1SLC28A1SLC28A2
SCHEMBL263750 0.81 DNPH1 (0.71) PYGMTK2DNPH1SLC28A1SLC28A2
SCHEMBL14946378 0.81 DNPH1 (0.71) PYGMTK2DNPH1SLC28A1SLC28A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015051173-A2 POLYNUCLEOTIDE MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC (US) 2015-04-09 — — WO disclosed