SCHEMBL263750

SCHEMBL263750

O=c1[nH]c(=O)n([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)cc1CO

nearest known ligand 0.71

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DNPH1 O43598 1/20 0.71
PYGM P11217 3/20 0.70
TK2 O00142 3/20 0.65
SLC28A1 O00337 1/20 0.60
SLC28A2 O43868 1/20 0.60
SLC29A1 Q99808 1/20 0.60
SLC28A3 Q9HAS3 1/20 0.60
P2RY2 P41231 4/20 0.51
TK1 P04183 1/20 0.48
MAPT P10636 1/20 0.48
CDA P32320 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14853793 1.00 DNPH1 (0.71) DNPH1PYGMTK2SLC28A1SLC28A2
SCHEMBL263751 1.00 DNPH1 (0.71) DNPH1PYGMTK2SLC28A1SLC28A2
SCHEMBL14946378 1.00 DNPH1 (0.71) DNPH1PYGMTK2SLC28A1SLC28A2
SCHEMBL9465821 1.00 DNPH1 (0.71) DNPH1PYGMTK2SLC28A1SLC28A2
SCHEMBL14929135 1.00 DNPH1 (0.71) DNPH1PYGMTK2SLC28A1SLC28A2
SCHEMBL13519201 0.99 PYGM (0.73) DNPH1PYGMTK2SLC28A1SLC28A2
Uridine SCHEMBL29084594 0.91 SLC28A1 (0.78) DNPH1PYGMTK2SLC28A1SLC28A2
SCHEMBL1286250 0.91 PYGM (0.69) DNPH1PYGMTK2SLC28A1SLC28A2
SCHEMBL2577325 0.91 PYGM (0.69) DNPH1PYGMTK2SLC28A1SLC28A2
SCHEMBL1286252 0.91 PYGM (0.69) DNPH1PYGMTK2SLC28A1SLC28A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 716 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12618064-B2 Acetylated ribonucleic acids and uses thereof HELIX NANOTECHNOLOGIES INC (US) 2026-05-05 US claimed
US-20260108554-A1 METHODS FOR REPROGRAMMING AND GENE EDITING CELLS FACTOR BIOSCIENCE INC (US) 2026-04-23 US claimed
EP-4720279-A2 CIS-REGULATORY ELEMENTS OF TRANSLATION AND METHODS USING SAME Yale University (US) 2026-04-08 EP claimed
EP-4716748-A2 METHOD OF MODULATING MRNA TRANSLATION Yale University (US) 2026-04-01 EP claimed
US-20260078356-A1 COMPOSITIONS AND METHODS FOR TREATING ORNITHINE TRANSCARBAMYLASE DEFICIENCY ARCTURUS THERAPEUTICS INC (US) 2026-03-19 US claimed
US-12551551-B2 Compositions comprising α-factor prepro sequence and uses thereof HELIX NANOTECHNOLOGIES INC (US) 2026-02-17 US claimed
US-12509698-B2 Synthesis and structure of high potency RNA therapeutics ARCTURUS THERAPEUTICS, INC. (US) 2025-12-30 US claimed
EP-4665405-A1 DNA COMPOSITIONS COMPRISING MODIFIED URACIL Flagship Pioneering Innovations VII, LLC (US) 2025-12-24 EP claimed
US-20250346888-A1 PROMOTER PROXIMAL SEQUENCES AND USES THEREOF FOR RNA MANUFACTURING HELIX NANOTECHNOLOGIES INC (US) 2025-11-13 US claimed
EP-4619531-A1 SELF-REPLICATING RNA AND USES THEREOF Trustees of Boston University (US) 2025-09-24 EP claimed
US-8822146-B2 Derivatization of biomolecules by covalent coupling of non-cofactor compounds using methyltransferases VILNIUS UNIVERSITY (LT) 2014-09-02 US claimed
EP-2414528-B1 DERIVATIZATION OF BIOMOLECULES BY COVALENT COUPLING OF NON-COFACTOR COMPOUNDS USING METHYLTRANSFERASES UNIV VILNIUS (LT) 2014-05-07 EP claimed
US-20120094280-A1 DERIVATIZATION OF BIOMOLECULES BY COVALENT COUPLING OF NON-COFACTOR COMPOUNDS USING METHYLTRANSFERASES BIOTECHNOLOGIJOS INSTITUTAS (LT) 2012-04-19 US claimed
EP-0653439-B1 Stabilized oligonucleotids and the use thereof AVENTIS PHARMA GMBH (DE) 2004-04-28 EP claimed
EP-0661291-B1 Solid phase synthesis of oligoribonucleotide AVENTIS PHARMA GMBH (DE) 2001-03-07 EP claimed
US-5652358-A Solid-phase synthesis of oligoribonucleotides HOECHST AKTIENGESELLSCHAFT (DE) 1997-07-29 US claimed
EP-0770144-A1 NUCLEIC ACID AMPLIFICATION METHOD USING A MODIFIED NUCLEOSIDE, AND DETECTION OF THE AMPLIFICATION PRODUCT USING ANTIBODIES PARTEUROP DEVELOPPEMENT (FR) 1997-05-02 EP claimed
WO-1996003526-A1 NUCLEIC ACID AMPLIFICATION METHOD USING A MODIFIED NUCLEOSIDE, AND DETECTION OF THE AMPLIFICATION PRODUCT USING ANTIBODIES PARTEUROP DEVELOPPEMENT (FR) 1996-02-08 WO claimed
EP-0661291-A1 Solid phase synthesis of oligoribonucleotide HOECHST AKTIENGESELLSCHAFT (DE) 1995-07-05 EP claimed
EP-0653439-A2 Stabilized oligonucleotids and the use thereof HOECHST AKTIENGESELLSCHAFT (DE) 1995-05-17 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108554-A1 METHODS FOR REPROGRAMMING AND GENE EDITING CELLS B2M, MYADM, CD74 DNPH1 3129/4885PYGM 1074/4885TK2 1615/4885
US-12509698-B2 Synthesis and structure of high potency RNA therapeutics IGF2BP3, SERPINC1, IGF2BP2 DNPH1 3822/4885PYGM 3892/4885TK2 1650/4885
US-20120094280-A1 DERIVATIZATION OF BIOMOLECULES BY COVALENT COUPLING OF NON-COFACTOR COMPOUNDS USING METHYLTRANSFERASES EZH1, DOHH, BHMT2 DNPH1 123/4885PYGM 1880/4885TK2 330/4885
US-12551551-B2 Compositions comprising α-factor prepro sequence and uses thereof UPF1, CPSF1, HM13 DNPH1 2954/4885PYGM 1524/4885TK2 1633/4885
US-12618064-B2 Acetylated ribonucleic acids and uses thereof RNMT, TRDMT1, TRMT1L DNPH1 2976/4885PYGM 1926/4885TK2 425/4885
US-20250346888-A1 PROMOTER PROXIMAL SEQUENCES AND USES THEREOF FOR RNA MANUFACTURING RNGTT, NSUN2, CPSF6 DNPH1 2996/4885PYGM 1876/4885TK2 1333/4885
US-20260078356-A1 COMPOSITIONS AND METHODS FOR TREATING ORNITHINE TRANSCARBAMYLASE DEFICIENCY OTC, OAT, POLRMT DNPH1 1163/4885PYGM 1852/4885TK2 59/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.