Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I3 | Q14994 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631462 | 0.82 | SMN1; SMN2 (0.36) | MAPTALDH1A1KDM4ESMN1; SMN2TP53 | |
| SCHEMBL18081957 | 0.78 | NR1I3 (0.41) | NR1I3MAPTALDH1A1KDM4ENR1I2 | |
| SCHEMBL16631527 | 0.74 | KMT2A (0.33) | NR1I3MAPTRXFP1 | |
| SCHEMBL16631709 | 0.74 | NR1I3 (0.41) | NR1I3MAPTALDH1A1KDM4ENR1I2 | |
| SCHEMBL18080481 | 0.74 | NR1I3 (0.35) | NR1I3MAPTALDH1A1KDM4ENR1I2 | |
| SCHEMBL18081960 | 0.68 | RAB9A (0.40) | MAPTALDH1A1KDM4ESMN1; SMN2GAA | |
| SCHEMBL16631705 | 0.67 | TNKS (0.33) | MAPTALDH1A1KDM4E | |
| SCHEMBL16631257 | 0.65 | SELP (0.33) | ADK | |
| SCHEMBL11644693 | 0.65 | SMN1; SMN2 (0.46) | MAPTALDH1A1KDM4ESMN1; SMN2TP53 | |
| SCHEMBL18080446 | 0.65 | NPC1 (0.32) | MAPTALDH1A1HSD17B10TP53GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |