Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 10/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631679 | 0.84 | KDM4E (0.38) | KDM4EALDH1A1HCAR2DGAT1CYP1A2 | |
| SCHEMBL18081918 | 0.82 | NOTUM (0.35) | KDM4EALDH1A1DGAT1CYP1A2CYP2C9 | |
| SCHEMBL18080475 | 0.78 | KDM4E (0.33) | KDM4EALDH1A1DGAT1CYP1A2CYP2C9 | |
| SCHEMBL16631474 | 0.75 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL16631746 | 0.73 | MAP4K1 (0.32) | HCAR2 | |
| SCHEMBL16631912 | 0.72 | HSP90AA1 (0.33) | HCAR2 | |
| SCHEMBL18081962 | 0.72 | NOTUM (0.34) | KDM4EALDH1A1DGAT1CYP1A2CYP2C9 | |
| SCHEMBL16631382 | 0.71 | NOTUM (0.36) | KDM4EALDH1A1DGAT1CYP1A2CYP2C9 | |
| SCHEMBL16631478 | 0.70 | HCAR2 (0.34) | HCAR2AR | |
| SCHEMBL16631411 | 0.68 | TNKS (0.36) | HCAR2CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |