Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.33 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631411 | 0.83 | TNKS (0.36) | TNKSPARP1TNKS2PARP2PARP3 | |
| SCHEMBL18081827 | 0.79 | NR1I3 (0.34) | MAPTALDH1A1 | |
| SCHEMBL18080497 | 0.75 | RPS6KA3 (0.31) | — | |
| SCHEMBL16631941 | 0.74 | MAPT (0.32) | MAPTKDM4EALDH1A1 | |
| SCHEMBL16631682 | 0.74 | KMT2A (0.33) | MAPT | |
| SCHEMBL16631709 | 0.73 | NR1I3 (0.41) | MAPTKDM4EALDH1A1 | |
| SCHEMBL16631707 | 0.73 | KMT2A (0.31) | MAPT | |
| SCHEMBL16631527 | 0.70 | KMT2A (0.33) | MAPT | |
| SCHEMBL18081931 | 0.69 | TNKS2 (0.34) | TNKSPARP1TNKS2PARP2PARP3 | |
| SCHEMBL16631679 | 0.69 | KDM4E (0.38) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |