Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18081968 | 0.85 | NR1I3 (0.33) | MAPT | |
| SCHEMBL16631745 | 0.84 | HCAR2 (0.34) | HCAR2 | |
| SCHEMBL18080511 | 0.78 | — | — | |
| SCHEMBL18081755 | 0.76 | HPGD (0.36) | MAPT | |
| SCHEMBL16631924 | 0.75 | NR1I3 (0.31) | — | |
| SCHEMBL16631705 | 0.74 | TNKS (0.33) | MAPT | |
| SCHEMBL16631709 | 0.72 | NR1I3 (0.41) | KMT2AMAPTRXFP1 | |
| SCHEMBL18080476 | 0.69 | PDE2A (0.34) | — | |
| SCHEMBL16631841 | 0.69 | PYGL (0.37) | MAPT | |
| SCHEMBL16631527 | 0.69 | KMT2A (0.33) | KMT2AMAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |