Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 3/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18081755 | 0.86 | HPGD (0.36) | TNKSTNKS2RAB9APARP2HPGD | |
| SCHEMBL16631682 | 0.84 | KMT2A (0.33) | HCAR2 | |
| SCHEMBL18080476 | 0.79 | PDE2A (0.34) | TNKSTNKS2PARP2HPGDHSD17B1 | |
| SCHEMBL16631454 | 0.77 | TNKS (0.34) | TNKSTNKS2RAB9APARP2HPGD | |
| SCHEMBL16631478 | 0.74 | HCAR2 (0.34) | HCAR2PDE3BPDE3AAR | |
| SCHEMBL18081968 | 0.74 | NR1I3 (0.33) | TNKSTNKS2PARP2HPGDPIN1 | |
| SCHEMBL16631411 | 0.73 | TNKS (0.36) | HCAR2TNKSTNKS2PARP2HPGD | |
| SCHEMBL16631471 | 0.71 | MAPK1 (0.37) | HPGD | |
| SCHEMBL16631495 | 0.68 | DAO (0.34) | RAB9AHPGD | |
| SCHEMBL18080511 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |