Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I3 | Q14994 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631471 | 0.82 | MAPK1 (0.37) | MAPTALDH1A1KDM4EGAAHSD17B10 | |
| SCHEMBL18081951 | 0.80 | NR1I3 (0.45) | NR1I3MAPTRXFP1NR1I2CYP1A2 | |
| SCHEMBL16631414 | 0.74 | NR1I3 (0.35) | NR1I3MAPTRXFP1NR1I2CYP1A2 | |
| SCHEMBL18080500 | 0.74 | NR1I3 (0.41) | NR1I3MAPTRXFP1NR1I2CYP1A2 | |
| SCHEMBL16631705 | 0.73 | TNKS (0.33) | MAPTALDH1A1KDM4E | |
| SCHEMBL16631937 | 0.73 | KDM4E (0.37) | MAPTRXFP1KMT2AALDH1A1KDM4E | |
| SCHEMBL16631682 | 0.72 | KMT2A (0.33) | MAPTRXFP1KMT2A | |
| SCHEMBL16631527 | 0.71 | KMT2A (0.33) | NR1I3MAPTRXFP1KMT2A | |
| SCHEMBL18081932 | 0.69 | MAPK1 (0.40) | MAPTALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL16631922 | 0.68 | L3MBTL1 (0.35) | MAPTRXFP1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |