Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631683 | 0.87 | MEN1 (0.30) | — | |
| SCHEMBL18081850 | 0.84 | — | — | |
| SCHEMBL16631759 | 0.84 | KMT2A (0.32) | ALDH1A1 | |
| SCHEMBL18080596 | 0.81 | KRAS (0.34) | — | |
| SCHEMBL18081915 | 0.76 | PDE3B (0.31) | — | |
| SCHEMBL16631754 | 0.73 | MEN1 (0.33) | KDM4EALDH1A1 | |
| SCHEMBL18080592 | 0.73 | KRAS (0.33) | — | |
| SCHEMBL16631765 | 0.72 | NPSR1 (0.33) | KDM4EALDH1A1 | |
| SCHEMBL16631764 | 0.72 | LMNA (0.33) | KDM4EALDH1A1 | |
| SCHEMBL18081851 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |