SCHEMBL16631958

SCHEMBL16631958

Nc1ccc2ccc(=O)nc-2[nH]1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.42
KMT2A Q03164 6/20 0.42
MAPT P10636 6/20 0.42
ALDH1A1 P00352 4/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
HPGD P15428 3/20 0.42
TNKS O95271 6/20 0.41
TNKS2 Q9H2K2 6/20 0.41
PARP1 P09874 5/20 0.41
RXFP1 Q9HBX9 2/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
KDM4E B2RXH2 4/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
GFER P55789 2/20 0.38
POLB P06746 2/20 0.38
HSD17B10 Q99714 2/20 0.38
GLA P06280 2/20 0.38
RECQL P46063 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1983843 0.75 MASP2 (0.39) MEN1KMT2AMAPTALDH1A1SMN1; SMN2
SCHEMBL4007504 0.72 CHEK2 (0.51) TNKSTNKS2PARP2
SCHEMBL4585526 0.70 NISCH (0.36) MEN1KMT2AMAPTALDH1A1SMN1; SMN2
SCHEMBL5887078 0.67 NPC1 (0.41) KMT2AMAPTALDH1A1SMN1; SMN2HPGD
SCHEMBL6436382 0.67 NISCH (0.41) MEN1KMT2AMAPTALDH1A1SMN1; SMN2
SCHEMBL7395689 0.64 MAPK14 (0.48) MEN1KMT2AMAPTALDH1A1SMN1; SMN2
SCHEMBL14831001 0.64 ADORA2A (0.32) ALDH1A1SMN1; SMN2KDM4EGAA
SCHEMBL15993522 0.62 SCD (0.39) KMT2AALDH1A1SMN1; SMN2HPGDNPC1
SCHEMBL3480692 0.61
SCHEMBL5333920 0.61 MAPK1 (0.53) MEN1KMT2AMAPTSMN1; SMN2TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118498092-A Oiling agent for aramid fiber and application thereof 东华大学 2024-08-16 CN claimed
CN-117551267-B Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 武汉柔显科技股份有限公司 2024-04-19 CN disclosed
CN-117551267-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 武汉柔显科技股份有限公司 2024-02-13 CN disclosed
US-20160264614-A1 POLYNUCLEOTIDE MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2016-09-15 US disclosed
WO-2015051173-A2 POLYNUCLEOTIDE MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC (US) 2015-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160264614-A1 POLYNUCLEOTIDE MOLECULES AND USES THEREOF POLRMT, POLN, NSUN3 MEN1 3881/4885KMT2A 3598/4885MAPT 3290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.