Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 11/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16632540 | 0.91 | RORC (0.51) | RORC | |
| SCHEMBL16632547 | 0.79 | RORC (0.65) | RORC | |
| SCHEMBL15202391 | 0.73 | SRD5A2 (0.43) | — | |
| SCHEMBL15201993 | 0.72 | SRD5A2 (0.50) | — | |
| SCHEMBL16461153 | 0.71 | RORC (0.70) | RORC | |
| SCHEMBL16632824 | 0.71 | RORC (0.49) | RORC | |
| SCHEMBL16632587 | 0.70 | RORC (0.70) | RORC | |
| SCHEMBL16633002 | 0.69 | RORC (0.69) | RORC | |
| SCHEMBL14108718 | 0.67 | GPR52 (0.50) | GPR52GRIA2GRIN1GRIN2A | |
| SCHEMBL16460149 | 0.67 | RORC (0.45) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3560920-A1 | SECONDARY ALCOHOL QUINOLINYL MODULATORS OF ROR GAMMA T | Janssen Pharmaceutica NV (BE) | 2019-10-30 | — | — | EP | disclosed |
| EP-3057949-B1 | SECONDARY ALCOHOL QUINOLINYL MODULATORS OF ROR GAMMA T | JANSSEN PHARMACEUTICA NV (BE) | 2019-06-05 | — | — | EP | disclosed |
| US-9221804-B2 | Secondary alcohol quinolinyl modulators of RORγt | JANSSEN PHARMACEUTICA NV (BE) | 2015-12-29 | — | — | US | disclosed |
| US-9221804-B2 | Secondary alcohol quinolinyl modulators of RORγt | JANSSEN PHARMACEUTICA NV (BE) | 2015-12-29 | — | — | US | disclosed |
| US-9221804-B2 | Secondary alcohol quinolinyl modulators of RORγt | JANSSEN PHARMACEUTICA NV (BE) | 2015-12-29 | — | — | US | disclosed |
| US-20150105372-A1 | SECONDARY ALCOHOL QUINOLINYL MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-16 | — | — | US | disclosed |
| US-20150105372-A1 | SECONDARY ALCOHOL QUINOLINYL MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-16 | — | — | US | disclosed |
| US-20150105372-A1 | SECONDARY ALCOHOL QUINOLINYL MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105372-A1 | SECONDARY ALCOHOL QUINOLINYL MODULATORS OF RORyt | RORC, RORA, RORB | RORC 1/4885NTRK1 1722/4885GPR52 202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.