Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.59 |
| ▸ | CDK1 | P06493 | 1/20 | 0.59 |
| ▸ | CDK4 | P11802 | 1/20 | 0.59 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.59 |
| ▸ | CCND1 | P24385 | 1/20 | 0.59 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.50 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29537861 | 0.90 | CCNB2 (0.72) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL433401 | 0.90 | CCNB2 (0.72) | CCNB2CDK1CDK4CCNB1CCND1 | |
| Fluoride SCHEMBL27920182 | 0.88 | CCNB2 (0.70) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL24631770 | 0.87 | CCNB2 (0.50) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL28184451 | 0.85 | CCNB2 (0.58) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL30134837 | 0.84 | CCNB2 (0.47) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL24631388 | 0.84 | CCNB2 (0.47) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL16632400 | 0.84 | CCNB2 (0.47) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL24631587 | 0.84 | CCNB2 (0.47) | CCNB2CDK1CDK4CCNB1CCND1 | |
| SCHEMBL16632374 | 0.84 | PTGER1 (0.48) | CCNB2CDK1CDK4CCNB1CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838889-B1 | LICHESTERINIC ACID AND THE DERIVATIVES OF SAME AS PIGMENTATION INHIBITORS | CENTRE NAT DE LA RECH SCIENT (C N R S ) (FR) | 2017-05-03 | — | — | EP | claimed |
| US-9265706-B2 | Lichesterinic acid and the derivatives of same as pigmentation inhibitors | Centre National de la Recherche Scientifique—CNRS (FR) | 2016-02-23 | — | — | US | claimed |
| US-20150105459-A1 | LICHESTERINIC ACID AND THE DERIVATIVES OF SAME AS PIGMENTATION INHIBITORS | UNIVERSITE DE RENNES (FR) | 2015-04-16 | — | — | US | claimed |
| US-9382245-B2 | Compounds and methods for treating HIV infections | YALE UNIVERSITY (US) | 2016-07-05 | — | — | US | disclosed |
| US-9265706-B2 | Lichesterinic acid and the derivatives of same as pigmentation inhibitors | Centre National de la Recherche Scientifique—CNRS (FR) | 2016-02-23 | — | — | US | disclosed |
| US-20150105459-A1 | LICHESTERINIC ACID AND THE DERIVATIVES OF SAME AS PIGMENTATION INHIBITORS | UNIVERSITE DE RENNES (FR) | 2015-04-16 | — | — | US | disclosed |
| US-20150105351-A1 | COMPOUNDS AND METHODS FOR TREATING HIV INFECTIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105459-A1 | LICHESTERINIC ACID AND THE DERIVATIVES OF SAME AS PIGMENTATION INHIBITORS | TYR, MITF, ALDH7A1 | CCNB2 2719/4885CDK1 1114/4885CDK4 2775/4885 |
| US-20150105351-A1 | COMPOUNDS AND METHODS FOR TREATING HIV INFECTIONS | POLM, POLRMT, DHFR | CCNB2 3282/4885CDK1 2209/4885CDK4 1497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.