Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16461511 | 0.85 | RORC (0.75) | RORC | |
| SCHEMBL16632708 | 0.85 | RORC (0.58) | RORC | |
| SCHEMBL16632361 | 0.84 | RORC (0.59) | RORC | |
| SCHEMBL16632362 | 0.83 | RORC (0.51) | RORC | |
| SCHEMBL16641815 | 0.80 | RORC (0.54) | RORC | |
| SCHEMBL16641802 | 0.80 | RORC (0.68) | RORC | |
| SCHEMBL16641803 | 0.78 | RORC (0.60) | RORC | |
| SCHEMBL21075978 | 0.77 | RORC (0.50) | RORC | |
| SCHEMBL16641820 | 0.77 | RORC (0.59) | RORC | |
| SCHEMBL21075983 | 0.77 | RORC (0.55) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057951-B1 | METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | JANSSEN PHARMACEUTICA NV (BE) | 2019-11-20 | — | — | EP | disclosed |
| EP-3560920-A1 | SECONDARY ALCOHOL QUINOLINYL MODULATORS OF ROR GAMMA T | Janssen Pharmaceutica NV (BE) | 2019-10-30 | — | — | EP | disclosed |
| EP-3057949-B1 | SECONDARY ALCOHOL QUINOLINYL MODULATORS OF ROR GAMMA T | JANSSEN PHARMACEUTICA NV (BE) | 2019-06-05 | — | — | EP | disclosed |
| EP-3057949-B1 | SECONDARY ALCOHOL QUINOLINYL MODULATORS OF ROR GAMMA T | JANSSEN PHARMACEUTICA NV (BE) | 2019-06-05 | — | — | EP | disclosed |
| US-9284308-B2 | Methylene linked quinolinyl modulators of RORγt | JANSSEN PHARMACEUTICA NV | 2016-03-15 | — | — | US | disclosed |
| US-9284308-B2 | Methylene linked quinolinyl modulators of RORγt | JANSSEN PHARMACEUTICA NV | 2016-03-15 | — | — | US | disclosed |
| US-9221804-B2 | Secondary alcohol quinolinyl modulators of RORγt | JANSSEN PHARMACEUTICA NV (BE) | 2015-12-29 | — | — | US | disclosed |
| US-9221804-B2 | Secondary alcohol quinolinyl modulators of RORγt | JANSSEN PHARMACEUTICA NV (BE) | 2015-12-29 | — | — | US | disclosed |
| US-9221804-B2 | Secondary alcohol quinolinyl modulators of RORγt | JANSSEN PHARMACEUTICA NV (BE) | 2015-12-29 | — | — | US | disclosed |
| US-20150105366-A1 | METHYLENE LINKED QUINOLINYL MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-16 | — | — | US | disclosed |
| US-20150105366-A1 | METHYLENE LINKED QUINOLINYL MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-16 | — | — | US | disclosed |
| US-20150105372-A1 | SECONDARY ALCOHOL QUINOLINYL MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-16 | — | — | US | disclosed |
| US-20150105366-A1 | METHYLENE LINKED QUINOLINYL MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-16 | — | — | US | disclosed |
| US-20150105372-A1 | SECONDARY ALCOHOL QUINOLINYL MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-16 | — | — | US | disclosed |
| US-20150105372-A1 | SECONDARY ALCOHOL QUINOLINYL MODULATORS OF RORyt | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105366-A1 | METHYLENE LINKED QUINOLINYL MODULATORS OF RORyt | RORC, RORA, RORB | RORC 1/4885 |
| US-20150105372-A1 | SECONDARY ALCOHOL QUINOLINYL MODULATORS OF RORyt | RORC, RORA, RORB | RORC 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.