Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | PER2 | O15055 | 1/20 | 0.36 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.36 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2384890 | 0.90 | KCNN4 (0.45) | KCNN4KCNA5MTNR1AMTNR1BENPP2 | |
| SCHEMBL14034634 | 0.86 | KCNN4 (0.50) | KCNN4KCNA5SLC6A4 | |
| SCHEMBL16633229 | 0.84 | KCNN4 (0.43) | KCNN4KCNA5MTNR1AMTNR1BENPP2 | |
| SCHEMBL14034702 | 0.83 | KCNN4 (0.48) | KCNN4KCNA5HTR7 | |
| SCHEMBL16633053 | 0.82 | GFER (0.46) | KCNN4KCNA5ENPP2GSK3BPER2 | |
| SCHEMBL27940602 | 0.81 | KCNN4 (0.45) | KCNN4KCNA5ENPP2GSK3BPER2 | |
| SCHEMBL10019235 | 0.81 | KCNN4 (0.45) | KCNN4KCNA5ENPP2GSK3BPER2 | |
| SCHEMBL14034729 | 0.78 | KCNN4 (0.48) | KCNN4KCNA5ENPP2GSK3BPER2 | |
| SCHEMBL14155119 | 0.78 | KCNN4 (0.43) | KCNN4KCNA5ENPP2PER2CRY1 | |
| SCHEMBL6476823 | 0.78 | KCNA5 (0.46) | KCNN4KCNA5MTNR1AMTNR1BGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238632-B2 | 3-cyanoanilinoalkylarylpiperazine derivative and use thereof in preparing drugs | NHWA Pharma, Corporation (CN) | 2016-01-19 | — | — | US | disclosed |
| CN-103360342-B | 3-cyano-aniline alkylaryl bridged piperazine derivatives and preparing the application in medicine | JIANGSU NHWA PHARMACEUTICAL CO., LTD. (CN) | 2015-12-16 | — | — | CN | disclosed |
| US-20150105399-A1 | 3-CYANOANILINOALKYLARYLPIPERAZINE DERIVATIVE AND USE THEREOF IN PREPARING DRUGS | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2015-04-16 | — | — | US | disclosed |
| CN-103360342-A | 3-Cyanoaniline alkyl aryl piperazine derivative and application in preparing medicaments | JIANGSU NHWA PHARMACEUTICAL CO LTD | 2013-10-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105399-A1 | 3-CYANOANILINOALKYLARYLPIPERAZINE DERIVATIVE AND USE THEREOF IN PREPARING DRUGS | HTR5A, HTR3C, HTR3A | KCNN4 604/4885KCNA5 134/4885MTNR1A 811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.