Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PER2 | O15055 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8650222 | 0.84 | ALDH1A1 (0.53) | GFERKCNN4KCNA5ALDH1A1CYP3A4 | |
| SCHEMBL27921817 | 0.82 | KCNN4 (0.46) | GFERKCNN4KCNA5ALDH1A1CYP3A4 | |
| SCHEMBL16633470 | 0.82 | KCNN4 (0.43) | KCNN4KCNA5S1PR1ENPP2HTR7 | |
| SCHEMBL29002366 | 0.81 | KCNN4 (0.43) | GFERKCNN4KCNA5ALDH1A1S1PR1 | |
| SCHEMBL29871439 | 0.81 | KCNN4 (0.43) | GFERKCNN4KCNA5ALDH1A1S1PR1 | |
| SCHEMBL9446180 | 0.78 | ALDH1A1 (0.52) | GFERALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL3830265 | 0.77 | KCNN4 (0.47) | GFERKCNN4KCNA5ALDH1A1CYP3A4 | |
| SCHEMBL4333663 | 0.76 | TSHR (0.52) | ALDH1A1CYP3A4MEN1KMT2AUSP2 | |
| SCHEMBL2384890 | 0.75 | KCNN4 (0.45) | KCNN4KCNA5S1PR1ENPP2PER2 | |
| SCHEMBL16633106 | 0.74 | GFER (0.45) | GFERKCNN4KCNA5ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238632-B2 | 3-cyanoanilinoalkylarylpiperazine derivative and use thereof in preparing drugs | NHWA Pharma, Corporation (CN) | 2016-01-19 | — | — | US | disclosed |
| CN-103360342-B | 3-cyano-aniline alkylaryl bridged piperazine derivatives and preparing the application in medicine | JIANGSU NHWA PHARMACEUTICAL CO., LTD. (CN) | 2015-12-16 | — | — | CN | disclosed |
| US-20150105399-A1 | 3-CYANOANILINOALKYLARYLPIPERAZINE DERIVATIVE AND USE THEREOF IN PREPARING DRUGS | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2015-04-16 | — | — | US | disclosed |
| CN-103360342-A | 3-Cyanoaniline alkyl aryl piperazine derivative and application in preparing medicaments | JIANGSU NHWA PHARMACEUTICAL CO LTD | 2013-10-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105399-A1 | 3-CYANOANILINOALKYLARYLPIPERAZINE DERIVATIVE AND USE THEREOF IN PREPARING DRUGS | HTR5A, HTR3C, HTR3A | GFER 4073/4885KCNN4 604/4885KCNA5 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.