Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 3/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664348 | 0.85 | BLM (0.35) | ALDH1A1TSHRBLMPMP22CYP2D6 | |
| SCHEMBL1664003 | 0.80 | ALDH1A1 (0.40) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL1666301 | 0.80 | ALDH1A1 (0.40) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL2010558 | 0.71 | CYP3A4 (0.36) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL2014071 | 0.67 | CTSL (0.35) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL1663428 | 0.67 | ALDH1A1 (0.35) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL16344589 | 0.66 | CETP (0.50) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL1664415 | 0.66 | ALDH1A1 (0.37) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL1664274 | 0.65 | ALDH1A1 (0.39) | ALDH1A1TSHRCYP3A4MAPK1TDP1 | |
| SCHEMBL1663376 | 0.65 | ALDH1A1 (0.51) | ALDH1A1TSHRCYP3A4MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307476-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009152068-A1 | ASYMMETRIC CYCLIC DIESTER COMPOUNDS | FERRO CORPORATION (US) | 2009-12-17 | — | — | WO | disclosed |